منابع مشابه
Whole Genome Sequencing in Cancer Clinics
Patients with a family history of cancer are being evaluated with consistentwith a RTS diagnosis. Themissense variant PRSS1 p.N29I is presingle-gene or gene panel tests (LaDuca et al., 2014). The decreasing cost and potential to provide comprehensive genetic risk assessment makes whole genome sequencing (WGS) an attractive tool for understanding the genetic risk for cancer (Collins and Hamburg,...
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Apoptosis, a form of programmed cell death, is a highly regulated process, the deregulation of which has been associated with the tumor initiation, progression, and metastasis in various cancers including breast cancer. Induction of apoptosis is a popular target of various therapies currently being tested or used for breast cancer treatment. Thus, identifying apoptotic mediators and regulators ...
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The increasing demand for genetic assessment for familial breast cancer has necessitated the development of cancer genetics services. However, little is known about the factors motivating the client population likely to approach these services. A cross sectional questionnaire survey of 1000 women with a family history of breast cancer was conducted to identify self-reported reasons for attendin...
متن کاملCancer, Senescence, and Aging: Translation from Basic Research to Clinics
1Oncoloǵıa y Patoloǵıa Grupo, Vall d’Hebron Institut de Recerca, 08035 Barcelona, Spain 2Unitat de Recerca Biomédica, Instituto de Biomedicina de Sevilla, 41013 Sevilla, Spain 3Genomic Stability Laboratory, Leibniz Institute for Age Research, 07745 Jena, Germany 4Genome High-Throughput Sequencing Laboratory, Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv Uni...
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This interesting issue in which the Institute of Oncology “Prof. Dr. Ion Chiricuta” of Cluj and the Cancer Institute “G. Paolo II” of Bari approach the problem of cancer biomarkers from different perspectives represents an attempt to provide a novel view of biological, clinical and methodological innovative aspects in this field. In fact, there is a critical need for reliable biomarkers in canc...
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ژورنال
عنوان ژورنال: CA: A Cancer Journal for Clinicians
سال: 1951
ISSN: 0007-9235
DOI: 10.3322/canjclin.1.3.94